Two new studies released early Wednesday show that
AIDS drugs can prevent heterosexuals from acquiring HIV, adding to a growing
number of new methods to slow the spread of the virus world-wide. Many
researchers now believe that science has developed sufficient tools to contain
the pandemic. But tight budgets may limit their deployment. The results are the
latest to soccer
jersey demonstrate that existing medications are an important
tool for prevention as well as treatment of HIV/AIDS, and show their
effectiveness in the population hardest hit by HIV globally—heterosexuals in
Africa.
The findings also are likely to help alleviate
concerns that emerged in April after another study was unable to determine
whether the drugs protected high-risk women. Both of the new studies, conducted
in different African countries, found that giving antiretroviral drugs to
heterosexuals reduced the risk of HIV infection by at least 62%—”which is
huge,” said Jared Baeten, co-chair of a study led by researchers at the
University of Washington International Clinical Research Center. That study
examined 4,758 heterosexual couples in NATIONAL
TEAM football shirt Kenya and Uganda in which one partner had HIV but
the other didn’t. Researchers found that those who received a daily dose of a
drug called tenofovir had an average of 62% fewer infections than those taking
a placebo, while those who received a drug combining tenofovir and another
medication, emtricitabine, had an average of 73% fewer infections. The drugs are
marketed by Gilead Sciences Inc. under the brand names Viread and Truvada,
respectively.
The study, funded by the Bill & Melinda Gates
Foundation, wasn’t supposed to end until late 2012. But after reviewing ongoing
results, an independent Data and Safety Monitoring Board decided Sunday to halt
the trial early because the findings were so strong, Dr. Baeten said. “We’re
stopping a year and a half early—really, on a dime—because the results were so
powerful,” Dr. Baeten said. Trial participants who were receiving placebo will
stop getting it on Thursday, and they will be offered the chance to Mexico
National Soccer Jersey take either of the antiretroviral
medicines, Dr. Baeten said. A separate study led by the Centers for Disease
Control and Prevention of 1,200 uninfected heterosexual men and women in
Botswana found that those taking a once-daily dose of Truvada reduced their
risk of acquiring HIV by about 63% compared to those taking a placebo. CDC
researchers believe the results may be even stronger among participants who
adhered closely to the regimen.
“This is exciting news for HIV prevention both within
the U.S. and globally,” said Kevin Fenton, director of the CDC’s National Center
for HIV/AIDS, Viral Hepatitis, STD and TB Prevention. “We’re beginning to
understand that these antiretroviral drugs are powerful tools for prevention
toolkits.” The CDC had planned to Mexico
football shirts release the results of its four-year study, which
it finished earlier this year, at an international AIDS conference in Rome next
week. But it accelerated its release to coincide with the other study results,
Dr. Fenton said.